Enterobacterales, Carbapenem-Resistant (all genera)
Infectious agent: Enterobacterales is an order comprised of gram-negative rod facultative anaerobes.
Other Common Genera:
Less Common Genera :
Description of illness: Enterobacterales cause a wide range of clinical infections and are a major cause of nosocomial infections. CRE include any organism that falls under the Enterobacterales order that are non-susceptible to carbapenem antibiotics and can cause infections with high rates of morbidity and mortality, particularly among persons with prolonged hospitalization, those who are critically ill, and those exposed to invasive devices (e.g., ventilators or central venous catheters). Symptoms may manifest thru respiratory, wound, urinary tract, invasive, tissue, and other infections. Some CRE have shown to be resistant to all or nearly all available antibiotics and therefore are classified by the Centers for Disease Control and Prevention (CDC) as an urgent threat.
- Facility Guidance for Control of Carbapenem-resistant Enterobacterales (CRE) – November 2015 CRE Toolkit